Abstract- Mobile WiMAX system is expected to be a base for wireless ubiquity products all over the world. this high mobility communication systems need eficient channel estimation to cope high frequency selectivity and time variation channel effect.there are two types of channel estimation based on the symbol used for pilot data, preamble symbol or data symbol. for the data symbol base channel estimation, we compare several interpolation methods (linear, 2nd order polynominal, lagrance, lowpass and wiener filter inerpolation) for derive channel response at all subcarrier and then conclude an efficient and suitable scheme for the cinsidered system. the performance of all methodes are showed by measuring bit error rate with 64 QAM and QPSK as modulation scheme and ITU A and ITU B vehicular channel as channel models.